The Chagas Disease Foundation

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Chagas disease is a debilitating and often fatal disease resulting from infection with the protozoan parasite Trypanosoma cruzi. The infection affects up to 20 million people in Mexico, Central America, and South America, making Chagas disease the highest impact infectious disease in Latin America. In addition to being a disease of poverty, Chagas disease is also poverty-promoting in striking hardest in young adults. Chagas disease has recently gained some notoriety in the United States due to both endogenous ("home-grown") and imported cases, prompting concern about the safety of blood and organ/tissue donations. Although 2009 marks the 100 year anniversary of the discovery of Chagas disease, the diagnosis, treatment and prevention of this infection are all highly inadequate.  The battle against Chagas disease begins with information and education.    More about Chagas Disease

Chagas Research Worldwide

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The Chagas Research Map Repository seeks to catalog global research efforts on Chagas disease.  Use the orientation tools to identify sites in particular areas, or launch the full map and use search terms to find sites of interest.  Browse individual research groups to learn more about their interests and needs.

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Research Spotlight

Behavioural physiology of Chagas disease vectors
Institut de Recherche sur la Biologie de l'Insecte, Tours
Tours, France

To better understand the physiology and behaviour of Chagas disease vectors.

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Recent Studies

Evaluation of CD4+CD25+ T lymphocyte response time kinetics in patients with chronic Chagas disease after in vitro stimulation with recombinant Trypanosoma cruzi antigens.
Braz SC, Lorena VM, Melo AS, Cavalcanti MD, Gomes YD

Outbreak of acute Chagas disease associated with oral transmission in the Rio Negro region, Brazilian Amazon.
Souza-Lima RD, Barbosa MD, Coura JR, Arcanjo AR, Nascimento AD, Ferreira JM, Magalhães LK, Albuquerque BC, Araújo GA, Guerra JA

Protection of vascular endothelium by aspirin in a murine model of chronic Chagas' disease.
Molina-Berríos A, Campos-Estrada C, Lapier M, Duaso J, Kemmerling U, Galanti N, Ferreira J, Morello A, López-Muñoz R, Maya JD

Anti-infective potential of marine invertebrates and seaweeds from the brazilian coast.
Bianco EM, de Oliveira SQ, Rigotto C, Tonini ML, da Rosa Guimarães T, Bittencourt F, Gouvêa LP, Aresi C, de Almeida MT, Moritz MI, Martins CD, Scherner F, Carraro JL, Horta PA, Reginatto FH, Steindel M, Simões CM, Schenkel EP

Trypanocidal activity of 1,3,7-trihydroxy-2-(3-methylbut-2-enyl)-xanthone isolated from Kielmeyera coriacea.
de Oliveira Caleare A, Lazarin-Bidóia D, Cortez DA, Ueda-Nakamura T, Dias Filho BP, de Oliveira Silva S, Nakamura CV

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