The Chagas Disease Foundation

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Chagas disease is a debilitating and often fatal disease resulting from infection with the protozoan parasite Trypanosoma cruzi. The infection affects up to 20 million people in Mexico, Central America, and South America, making Chagas disease the highest impact infectious disease in Latin America. In addition to being a disease of poverty, Chagas disease is also poverty-promoting in striking hardest in young adults. Chagas disease has recently gained some notoriety in the United States due to both endogenous ("home-grown") and imported cases, prompting concern about the safety of blood and organ/tissue donations. Although 2009 marks the 100 year anniversary of the discovery of Chagas disease, the diagnosis, treatment and prevention of this infection are all highly inadequate.  The battle against Chagas disease begins with information and education.    More about Chagas Disease

Chagas Research Worldwide

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The Chagas Research Map Repository seeks to catalog global research efforts on Chagas disease.  Use the orientation tools to identify sites in particular areas, or launch the full map and use search terms to find sites of interest.  Browse individual research groups to learn more about their interests and needs.

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Research Spotlight

Rio de Janeiro
Rio de janeiro, Brazil

To study though in silico methods active compounds to treat Chagas Disease

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Recent Studies

Kinome siRNA screen identifies novel cell-type specific dengue host target genes.
Kwon YJ, Heo J, Wong HE, Cruz DJ, Velumani S, da Silva CT, Mosimann AL, Duarte Dos Santos CN, Freitas-Junior LH, Fink K

Hologram QSAR Studies of Antiprotozoal Activities of Sesquiterpene Lactones.
Trossini GH, Maltarollo VG, Schmidt TJ

Therapeutic responses to different anti-Trypanosoma cruzi drugs in experimental infection by benznidazole-resistant parasite stock.
Caldas S, Caldas IS, Cecílio AB, Diniz LD, Talvani A, Ribeiro I, Bahia MT

Aspirin Modulates Innate Inflammatory Response and Inhibits the Entry of Trypanosoma cruzi in Mouse Peritoneal Macrophages.
Malvezi AD, da Silva RV, Panis C, Yamauchi LM, Lovo-Martins MI, Zanluqui NG, Tatakihara VL, Rizzo LV, Verri WA, Martins-Pinge MC, Yamada-Ogatta SF, Pinge-Filho P

Development and glycoprotein composition of the perimicrovillar membrane in Triatoma (Meccus) pallidipennis (Hemiptera: Reduviidae).
Gutiérrez-Cabrera AE, Alejandre-Aguilar R, Hernández-Martínez S, Espinoza B

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