Chagas Research WorldwideEnter your Research Facility
Immunobiology of Chagas Disease
UGA - Tarleton Lab
Athens, United States
We are broadly interested in immunity to Trypanosoma cruzi, and particularly in the role of CD8+ T cells in control of this infection. Other interests include development of improved diagnostics and methods for assessing treatment efficacy, vaccine development, and genomic, proteomic, transcriptomic and bioinformatic approaches to better understanding the biology of T. cruzi and combating Chagas disease.
Effect of secondary anchor amino acid substitutions on the immunogenic properties of an HLA-A*0201-restricted T cell epitope derived from the Trypanosoma cruzi KMP-11 protein.
Lasso P, Cárdenas C, Guzmán F, Rosas F, Thomas MC, López MC, González JM, Cuéllar A, Campanera JM, Luque FJ, Puerta CJ
Phthalimido-thiazoles as building blocks and their effects on the growth and morphology of Trypanosoma cruzi.
Gomes PA, Oliveira AR, Cardoso MV, Santiago EF, Barbosa MO, de Siqueira LR, Moreira DR, Bastos TM, Brayner FA, Soares MB, Mendes AP, de Castro MC, Pereira VR, Leite AC
Aberrant levels of Wnt/β-catenin pathway components in a rat model of endometriosis.
de Mattos RM, Pereira PR, Barros EG, da Silva JH, Palmero CY, da Costa NM, Pinto LF, Gimba ER, Medeiros FH, Ferreira LB, Machado DE, de Oliveira FL, Nasciutti LE
Inactivated poliovirus vaccine given alone or in a sequential schedule with bivalent oral poliovirus vaccine in Chilean infants: a randomised, controlled, open-label, phase 4, non-inferiority study.
O'Ryan M, Bandyopadhyay AS, Villena R, Espinoza M, Novoa J, Weldon WC, Oberste MS, Self S, Borate BR, Asturias EJ, Clemens R, Orenstein W, Jimeno J, Rüttimann R, Costa Clemens SA, Chilean IPV/bOPV study group
Intranasal vaccination with leishmanial antigens protects golden hamsters (Mesocricetus auratus) against Leishmania (Viannia) Braziliensis infection.
da Silva-Couto L, Ribeiro-Romão RP, Saavedra AF, da Silva Costa Souza BL, Moreira OC, Gomes-Silva A, Rossi-Bergmann B, Da-Cruz AM, Pinto EF